MSS 2/0134-01								Acc. 1990-093

 BROWN SEQUARD, C. E.,
(1817-1894)

 Writings,
 1890-1891

1. C. E. Brown Sequard
   ALS, Nice, France, 
   to [S. Weir Mitchell, Philadelphia, Pa.?],
   1890 Dec. 27					(1 item)		1890

2. Nouvelles remarques sur le suc testiculaire,
   [1890?], (3 p.).					(1 item)	    [1890?]

3. Histoire et critique : l'expose de faits nouveaux
   montrant la puissance de liquide testiculaire
   contre certaines maladies et en particulaire
   la tuberculose pulmonaire,
   [1891?], (6 p.).					(1 item)	    [1891?]

4. De la perte de connaissance dans l'epilepsie
   apres l'ablation du ganglion cervical superieur
   du nerf grand sympatique des deux cotes chez
   l'homme et chez le cobaye,
   [1891?], (3 p.).					(1 item)	    [1891?]


1890-1891
1 folder (4 items)

7/11/1990
jde

MSS 2/0134-01								Acc. 1990-093

 BROWN SEQUARD, C. E.,
(1817-1894)

 Writings,
 1890-1891

Biographical


Charles Edouard Brown Sequard, physiologist, was born on 8 April 
1817 on Mauritius.  He was married three times: to Ellen Fletcher 
(d. 1868) by whom he had one son; in 1873 to Maria R. Carlisle 
(d. 1875) by whom he had one daughter; and in 1878 to Elizabeth 
Emma Dakin.  Brown Sequard died on 1 April 1894.

Brown Sequard received a bachelor of letters and a bachelor of 
science from the University of Paris, then received an M.D. 
from the Ecole de Medecine in Paris in 1840.   He traveled extensively 
and held several teaching positions, including professor of 
physiology at the Medical College of Virginia, 1855, professor 
of physiology and pathology at Harvard University, 1864-1867, 
and professor of comparative and experimental pathology at the 
Ecole de Medecine in Paris, 1869-1871.  In 1873, he was practicing 
in New York, but in 1878 assumed the chair of experimental medicine 
at the College de France.  He also founded the Archives of scientific 
and practical medicine.

In 1849, Brown Sequard discovered sensory decussation in the spinal 
cord and worked for most of his life on diseases of the spinal 
column, nervous system, and muscular system.  In the last years 
of his life, Brown Sequard developed the popular "Methode Sequardienne", 
advocating the use of an extract of testicular fluid to rejuvenate 
the body, cure certain diseases, and prolong life.

Brown Sequard was a Fellow of the Royal College of Physicians 
of London, the Royal Society of England, and the American Academy 
of Sciences.


Scope and contents

This small collection contains three brief holograph manuscripts, 
1890-1891, of C. E. Brown Sequard.  Two of the manuscripts, 
"Nouvelles remarques" and "Histoire et critique" concern the 
therapeutic use of animal testicular extract as an aid to rejuvenation 
and a specific against diseases such as tuberculosis.  The third 
manuscript, "De la perte de connaissance" concerns epilepsy. 
 All three manuscripts were published, "Nouvelles remarques" 
in Comptes rendus hebdomadaires des seances 
et memoires la Societe de Biologie (1890), the other 
two in Archives de physiologiejnormale et 
pathologie (1891).

The collection also includes an autographed letter signed 
by Brown Sequard, 27 December 1890, conveying the three manuscripts 
to S. Weir Mitchell.


Provenance

The three Brown Sequard manuscripts were donated to the College 
of Physicians of Philadelphia by S. Weir Mitchell of Philadelphia 
on 13 January 1891.  On 27 December 1890, Brown Sequard himself 
sent the manuscripts to Mitchell, apparently at the latter's 
request, specifically for presentation to the College.


7/13/1990
jde